Home Effect of Tamarindus indica on Blood Pressure of Stage II Hypertensive Patients in a Tertiary Level Hospital

Effect of Tamarindus indica on Blood Pressure of Stage II Hypertensive Patients in a Tertiary Level Hospital

*Dr. Fatema-Tui-Johura, Medical Officer

Department of Pharmacology, Rangpur Medical College, Rangpur.
Email: [email protected]
Mobile: +8801717514875

Professor Md. Ismail Khan

Vice Chancellor, Chittagong Medical University, Chittagong

Prof. Eliza Omar Eva

Department of Pharmacology, Shaheed Suhrawardy Medical College, Dhaka

Dr. Masuma Khanam

Assistant Professor, Department of Pharmacology, Mugda Medical College, Dhaka

Dr. Mohammad Kamrul Hasan

Assistant Professor, Department of Pharmacology, Shaheed Tajuddin Ahmed Medical College, Gazipur.

Dr. Saugata Mitra

Lecturer, Department of Pharmacology, Pabna Medical College, Pabna.

Keywords: Tamarindus indica, Hypertension (HTN), Blood Pressure (BP)

Abstract

Background: Hypertension is recognized as one of the major contributors to the disease burden globally. Use of polypharmacy is a common phenomenon to treat moderate to severe hypertension. The burden of drug can be lessened by concomitant use of natural herbs that are easily available around us. Tamarindus indica which is locally known as tamarind, hasa wide range of medicinal application and positive effect on cardiovascular health.

Objective: To see the effect of Tamarindus indica on blood pressure of stage II hypertensive patients.

Methods: Patients with primary hypertension stage II attended in the outpatient department of medicine of Dhaka Medical College Hospital, were enrolled in the study. Among 90 participants, random allocation was done in test and control group where 45 participants were in test group and 45 participants were in control group. The pulverized pulp of Tamarindus indica fruit at a dose of 15 mg/kg/day had been given to the test group for 8 weeks along with drugs. The control group was only on drugs. Blood pressure was recorded at weekly interval in both test and control group. The results obtained from test group had been compared with that of control group.

Results: In case of control group systolic blood pressure was 123.88±3.45 mm of Hg and diastolic blood pressure was 78.55±3.16 mm of Hg. After taking tamarind for 8 weeks, mean the systolic and diastolic blood pressure of intervention group became 122.66±5.26 and 73.66±3.26 mm of Hg respectively. Though the fruits exerted no conspicuous effect on systolic blood pressure (p=0.19), it significantly reduced the diastolic pressure (p=0.001) as confirmed by independent sample t-test at 5% significance level.

Conclusion: Tamarindus indica reduced diastolic blood pressure in stage II hypertensive patients. In Bangladesh where hypertension shows a rising trend, the finding of the study definitely reveals a new dimension on the effect of fruits of Tamarindus indica on hypertension.