Morphological Variations of Weight & Volume of Prostate

CONTEXT: The prostate is a walnut sized fibromuscular glandular organ at the base of the urinary bladder. Prostate is the site of frequent medical problems affecting elderly men, benign prostatic hyperplasia (BPH), carcinoma prostate and prostatities. In order to plan appropriate treatment strategies of prostatic disease, studies on human prostate are expected to helpful for the urologist, pathologist and sonologist for diagnosis of disease .

OBJECTIVES: The objective of this study was to observe the morphological variarions of post mortem human prostate.

MATERIALS AND METHODS: The present study was carried out on 60 (sixty) human prostate collected from dead body those were under went post mortem examination of different age groups in Bangladeshi people and collected by consecutive, convenient and exhaustive sampling technique. All the specimens were studied macroscopically by careful dissection. A descriptive study was done in the department of Anatomy in collaboration of Forensic Medicine, Sylhet MAG Osmani Medical College, Sylhet from January 2015 to December 2015. The mean weight and volume of the prostates were 20.32 (SD ± 6.34) gm & 22.12 (SD ± 9.30) cm³. In this study, the weight and volume of prostates found significant positive correlation with age.

RESULTS: The weight of the prostate ranged from 7.80 gm to 31.30 gm with the mean 20.32 (SD ± 6.34) gm. The mean weight of the prostate were 11.29 gm (SD ± 2.60) (range 7.80-14.9 gm) in the age group of 10 to 20 years; 18.81 gm (SD ± 2.93) (range 14.40-24.80 gm) in the age group of 21 to 40 years and 27.08 gm (SD ± 2.73) (range 19.20-31.30 gm) in the age group of 41 to 70 years. The difference among the groups were statistically significant (F=6.755; p=0.011). The volume of the prostate ranged from 2.79 cm³ to 36.41 cm³ with the mean 22.12 (SD ± 9.30) cm³. The mean volume of prostate were 12.04 cm³ (SD ± 7.90) (range 2.79-26.73 cm³) in the age group of 10 to 20 years; 21.42 cm³ (SD ± 7.31) (range 11.34-33.98cm³) in the age group of 21 to 40 years and 28.33 cm³ (SD ± 7.42) (range 12.23-36.41 cm³) in the age group of 41 to 70 years. The difference among the groups were statistically significant (F=4.021; P=0.003).

CONCLUSION: In the present study weight and volume of the prostates had found significant positive correlation with age.